Thermo Fisher Scientific VIM Monoclonal Antibody (OTI1F10), TrueMAB
Vimentin 단백질을 타깃으로 하는 Mouse IgG2a 단클론 항체. Western blot에 최적화되어 있으며, 고순도의 Affinity chromatography 정제 제품. PBS, BSA, glycerol로 안정화되어 장기 보관 가능. 연구용으로만 사용.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F10 |
| Immunogen | Full length human recombinant protein of human VIM produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is involved in intracellular protein transport between the nucleus and plasma membrane. Vimentin, along with desmin, is expressed during early cellular development and later replaced by tissue-specific IFPs. It plays a role in steroid synthesis by acting as a storage network for cholesterol-containing lipid droplets. Phosphorylation of vimentin leads to cytoskeletal changes that facilitate lipid droplet interaction with mitochondria, promoting steroid synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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