Thermo Fisher Scientific MRPS18A Polyclonal Antibody
Human MRPS18A 단백질을 인식하는 Thermo Fisher의 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRPS18A. Recombinant protein control fragment (Product #RP-94658). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644184 |
Product Specific Information
Immunogen sequence:
PSELQRELQR LSPLPRHSGL LPNHRPRLPE GVVPKSKPQL NRYLTRWAPG SVKPIYKKGP RWNRVRMPVG SPLLRDNVCY SRTPWKLYH
Antigen sequence identity:
- Mouse: 65%
- Rat: 64%
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and assist in mitochondrial protein synthesis. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition, unlike prokaryotic ribosomes where this ratio is reversed. Prokaryotic ribosomes contain a 5S rRNA, which mammalian mitoribosomes lack.
The MRPS18A gene encodes a 28S subunit protein belonging to the ribosomal protein S18P family, one of three human mitochondrial S18 proteins showing sequence similarity to bacterial S18 proteins. A pseudogene corresponding to this gene is found on chromosome 3p. Alternative splicing yields multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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