Thermo Fisher Scientific XPF Monoclonal Antibody (OTI3H10), TrueMAB
ERCC4(XPF) 단백질을 인식하는 Mouse monoclonal antibody. Western blot, ICC/IF, Flow cytometry에 적합. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도. 다양한 종(Dog, Human, Mouse, Rat)에 반응하며, 연구용으로 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific XPF Monoclonal Antibody (OTI3H10), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H10 |
| Immunogen | Full length human recombinant protein of human ERCC4 produced in HEK293 cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
When using this carrier-free antibody for conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The structure-specific ERCC1/XPF endonuclease complex is involved in the repair of two distinct types of DNA lesions:
- NER (Nucleotide Excision Repair) for UV-induced lesions and bulky chemical adducts
- Recombination repair of genotoxic interstrand cross-links
In mammalian cells, XPG cleaves the 3′ side of the DNA lesion, while the ERCC1/XPF complex makes the 5′ incision.
ERCC1/XPF likely plays a role in processing partially repaired recombination intermediates.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.