Thermo Fisher Scientific GTP cyclohydrolase 1 Polyclonal Antibody, FITC
GTP cyclohydrolase 1 단백질을 인식하는 FITC 결합 폴리클로날 항체로, Western blot, ELISA, Immunoprecipitation 등에 사용 가능. 사람, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제. 연구용으로만 사용.
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Thermo Fisher Scientific GTP cyclohydrolase 1 Polyclonal Antibody, FITC
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | N-epitope synthetic peptide within amino acid region 1–50 of GTPCHI protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, containing 30% glycerol and 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 acts as an essential cofactor for aromatic amino acid hydroxylases and nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants produce a functional enzyme.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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