Thermo Fisher Scientific CTLA-4 Polyclonal Antibody
Mouse CTLA-4/CD152 특이적 Rabbit Polyclonal Antibody로, WB, ELISA, IP에 사용 가능. 비보존제 제품으로 장기보관 시 -20°C 권장. 고친화성 CTLA-4 결합 특성으로 면역억제 관련 연구에 적합.
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Thermo Fisher Scientific CTLA-4 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:25,000–1:50,000 |
| Immunoprecipitation (IP) | 1–2 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Mouse CTLA-4/CD152 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Lot-Specific |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long term storage store at -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2788580 |
Product Specific Information
- This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
- This antibody has specificity for Mouse CTLA-4/CD152.
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed mainly on CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells) but with higher affinity. Unlike CD28, which enhances T cell activation, CTLA4 inhibits T cell function and contributes to immune regulation. Intracellular CTLA4 is also found in regulatory T cells and is important for their suppressive activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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