Thermo Fisher Scientific Cathepsin A Polyclonal Antibody
Mouse Cathepsin A 특이적 Rabbit Polyclonal Antibody로 Western Blot, ELISA, Immunoprecipitation에 적합. Recombinant Cathepsin A 항원을 면역원으로 사용하며, 보존제 무첨가 액상 형태. 장기 보관 시 -20°C에서 보관 권장.
- 카탈로그번호
- PA581367
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 4–6 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Mouse Cathepsin A/CTSA protein (Met1–Tyr474) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788581 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Mouse Cathepsin A/CTSA.
Target Information
The cathepsin family of proteolytic enzymes includes several diverse classes of proteases. Cathepsins B, L, H, K, S, and O comprise the cysteine protease class; cathepsins D and E comprise the aspartyl protease class; and cathepsin G belongs to the serine protease class.
Cathepsins function in cellular metabolism and participate in peptide biosynthesis and protein degradation. Cathepsin A, a serine carboxypeptidase, exists in a high molecular weight lysosomal complex with β-galactosidase (β-gal) and α-neuraminidase (Neu1). Cathepsin A protects β-gal and Neu1 from intralysosomal proteolysis.
Deficiencies in cathepsin A lead to deficiencies in β-gal and Neu1. The gene encoding human cathepsin A maps to chromosome 20q13.12. Mutations in this gene cause galactosialidosis, a lysosomal storage disorder resulting from β-gal and Neu1 deficiencies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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