Thermo Fisher Scientific TdT Polyclonal Antibody
TdT 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot과 ELISA에 사용 가능. Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제. 핵 내 TdT 검출에 적합하며 연구용으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:100–1:500
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 260–509 of human TdT (NP_0040793) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.37 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806515 |
Product Specific Information
- Positive Samples: Mouse liver, Mouse thymus, Rat liver
- Cellular Location: Nucleus
Immunogen sequence:
LKTSEKWFRM GFRTLSKVRS DKSLKFTRMQ KAGFLYYEDL VSCVTRAEAE AVSVLVKEAV WAFLPDAFVT MTGGFRRGKK MGHDVDFLIT SPGSTEDEEQ LLQKVMNLWE KKGLLLYYDL VESTFEKLRL PSRKVDALDH FQKCFLIFKL PRQRVDSDQS SWQEGKTWKA IRVDLVLCPY ERRAFALLGW TGSRQFERDL RRYATHERKM ILDNHALYDK TKRIFLKAES EEEIFAHLGL DYIEPWERNA
Target Information
Terminal Deoxynucleotidyl Transferase (TdT) is a DNA polymerase located in the cell nucleus that catalyzes the polymerization of deoxynucleotides at the 3′ hydroxyl ends of oligo or polydeoxynucleotide initiators and functions without a template.
TdT is considered a highly specific marker for the diagnosis and classification of acute lymphoblastic lymphoma/leukemias.
Determination of TdT expression is particularly valuable for differentiating histologically between lymphoblastic lymphoma and Burkitt’s lymphoma.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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