Thermo Fisher Scientific M6PR Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 27-185 of human M6PR (NP_0023461) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:M6PR,uniProtId:P20645-1,ncbiNodeId:9606,antigenRange:27-185,antigenLength:277,antigenImageFileName:PA5-92876_M6PR_P20645-1_Rabbit.svg,antigenImageFileNamePDP:PA5-92876_M6PR_P20645-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.29 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806527

Product Specific Information

Immunogen sequence: TEEKTCDLVG EKGKESEKEL ALVKRLKPLF NKSFESTVGQ GSDTYIYIFR VCREAGNHTS GAGLVQINKS NGKETVVGRL NETHIFNGSN WIMLIYKGGD EYDNHCGKEQ RRAVVMISCN RHTLADNFNP VSEERGKVQD CFYLFEMDSS LACSPEISH; Positive Samples: Mouse kidney; Cellular Location: Lysosome membrane, Single-pass type I membrane protein

Target Information

M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.