
Thermo Fisher Scientific slo beta 2 (KCNMB2) Polyclonal Antibody
Rabbit polyclonal antibody against human and rat KCNMB2 (slo beta 2). Validated for WB and IHC. Lyophilized form, reconstitutable in DDW. High specificity via antigen affinity purification. Suitable for research use only.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:200 | |
| Immunohistochemistry (IHC) | Assay-dependent |
Product Specifications
| Category | Specification |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)RHDEKRNIYQKIRDHDLLD, corresponding to amino acid residues 14–32 of human KCNMB2, intracellular N-terminal domain |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 25 µL, 50 µL, or 0.2 mL of double distilled water (DDW) depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquot and store at -20°C.
Avoid multiple freeze/thaw cycles. Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
MaxiK channels are large conductance, voltage- and calcium-sensitive potassium channels essential for controlling smooth muscle tone and neuronal excitability. These channels consist of a pore-forming alpha subunit and a modulatory beta subunit.
The KCNMB2 gene encodes an auxiliary beta subunit that decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants, with additional variants described in literature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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