Thermo Fisher Scientific Kir4.1 (KCNJ10) Polyclonal Antibody, Atto 488

Applications

• Immunohistochemistry (Frozen) (IHC (F))
  Tested Dilution: 1:50

Product Specifications

Product Specific Information

• Reconstitution: Add 50 µL double distilled water (DDW), depending on sample size.
• Ships as lyophilized powder at room temperature; store at −20 °C upon arrival.
• Reconstituted solution stable at 4 °C for up to 1 week; for longer storage, aliquot and keep at −20 °C.
• Avoid multiple freeze/thaw cycles.
• Centrifuge all antibody preparations before use (10,000 × g, 5 min).

Target Information

The KIR (inwardly rectifying potassium channel) family allows potassium influx preferentially over efflux.
Kir4.1 (also known as Kir1.2) is highly expressed in brain tissue—glial cells, astrocytes, and cortical neurons—and plays a crucial role in myelination via oligodendrocytes.
Human KIR4.1 gene maps to chromosome 1.
Kir4.2 (Kir1.3) is expressed in kidney, lung, heart, thymus, and thyroid during development and may be involved in Down syndrome pathogenesis (chromosome 21).
Kir5.1 forms functional channels only when coexpressed with Kir4.1 or Kir4.2 in kidney and pancreas.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

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(이미지: APC-035-AG-50UL_Kir4.1_KCNJ10_P49655-1_Rabbit_PDP.jpeg)