Thermo Fisher Scientific CAD Polyclonal Antibody
Thermo Fisher Scientific의 CAD Polyclonal Antibody는 인간 CAD 단백질을 인식하는 토끼 다클론 항체입니다. Western blot과 IHC(Paraffin) 분석에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. PBS, 40% 글리세롤 완충액에 보관되며 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CAD. Recombinant protein control fragment (Product #RP-105473) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2662733 |
Product Specific Information
Immunogen sequence:
SHLPIVAHAEQ QTVAAVLMVA QLTQRSVHIC HVARKEEILL IKAAKARGLP VTCEVAPHHL FLSHDDLERL GPGKGEVRPE LGSRQDVEAL WENMAVIDCF ASDHAPHTLE EKCGSR
Highest antigen sequence identity to the following orthologs:
- Mouse: 89%
- Rat: 89%
Target Information
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein associated with the enzymatic activities of the first three enzymes in the six-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, indicating a direct link between MAPK activation and de novo biosynthesis of pyrimidine nucleotides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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