Thermo Fisher Scientific CNG4/GARP Polyclonal Antibody
CNG4/GARP 단백항체는 인간, 마우스, 랫트에서 반응하는 Rabbit Polyclonal IgG 항체입니다. IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, 고순도 Protein A 정제 및 안정적인 액상 형태로 제공됩니다. 냄새 신호 전달 연구에 활용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CNG4, amino acids 856–960 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Second messenger cAMP causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of olfactory sensory neurons (OSNs). CNGA4 is the modulatory subunit of this channel, playing a central role in odorant signal transduction and adaptation. By accelerating calcium-mediated negative feedback in olfactory signaling, it allows rapid adaptation to odor stimulation and extends the range of odor detection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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