
Thermo Fisher Scientific Cytokeratin 19 (KRT19) (Pancreatic Stem Cell Marker) Monoclonal Antibody (BA17)
Cytokeratin 19(KRT19)을 인식하는 마우스 단클론 항체로, 췌장 줄기세포 및 상피세포 마커 연구에 적합. Western blot, IHC, ICC, Flow Cytometry 등 다양한 응용 가능. Human 및 Mouse 시료 반응성. 단백질 A/G 정제, PBS 용액 형태로 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BA17 |
| Immunogen | Human mammary epithelial organoids |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratin 19 is part of the intermediate filament protein subfamily, characterized by biochemical diversity represented by at least 20 polypeptides in human epithelial tissues. Cytokeratins range in molecular weight from 40–68 kDa with isoelectric pH between 4.9 and 7.8.
Each cytokeratin subtype is numbered 1–20 and exhibits tissue-specific expression patterns, reflecting epithelial type and differentiation state. These expression profiles are valuable for distinguishing epithelial malignancies.
Cytokeratin antibodies are widely used in:
- Differential diagnosis of tumors via immunohistochemistry
- Cytopathology and flow cytometric assays
Notably, Cytokeratin 19 is not expressed in hepatocytes, making it useful for identifying liver metastases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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