Thermo Fisher Scientific DNAJA2 Polyclonal Antibody
Rabbit polyclonal antibody against human DNAJA2, validated for WB, IHC(P), and ICC/IF. High purity (>95%) and affinity-purified. Supplied as liquid at 1 mg/mL. Suitable for research use in protein folding and chaperone pathway studies.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human DNAJA2 (amino acids 1–412, UniProt ID: O60884-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C for short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720843 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum using an epitope-specific immunogen. Purity is >95% as determined by SDS-PAGE.
Target Information
The DNAJA2 protein belongs to the evolutionarily conserved DNAJ/HSP40 family, which regulates molecular chaperone activity by stimulating ATPase activity. DNAJ proteins typically contain:
- A conserved 70-amino acid J domain at the N-terminus
- A glycine/phenylalanine (G/F)-rich region
- A cysteine-rich domain with four zinc finger-like motifs
DNAJA2 functions as a cochaperone of Hsp70s, assisting in protein folding and mitochondrial protein import in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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