Thermo Fisher Scientific NDRG1 Polyclonal Antibody
인간 NDRG1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ELISA, IP에 사용 가능. 보존제가 없는 액상 형태이며, Protein A 및 항원 친화 정제. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10,000–1:20,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human NDRG1/CAP43 protein (Met1–Cys394) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788116 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human NDRG1/CAP43.
Target Information
NDRG1 is a 394 amino acid cytoplasmic protein belonging to the NDRG family. It interacts with APO A-I and A-II and plays a role in HDL-mediated cholesterol transport, stress responses, hormone responses, cell growth, and differentiation.
Defects in NDRG1 cause Charcot-Marie-Tooth disease type 4D (CMT4D), characterized by reduced nerve conduction velocities, segmental demyelination and remyelination with onion bulb formations, slowly progressive distal muscle atrophy and weakness, absent deep tendon reflexes, and hollow feet.
NDRG1 plays a growth inhibitory role and serves as a marker of differentiation. It is expressed in placental membranes, prostate, kidney, small intestine, ovary tissues, colon, and the cells that border the lumen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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