
Thermo Fisher Scientific GPR103 Polyclonal Antibody
GPR103 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human G protein coupled receptor 103 (amino acids 151–250) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
G protein-coupled receptors (GPRs) are a family of transmembrane receptors that transmit extracellular ligand signals into intracellular G protein activation. This signaling mechanism is conserved across eukaryotes for environmental sensing and cell communication.
All GPRs share seven membrane-spanning domains, with extracellular loops containing conserved cysteine residues forming disulfide bonds for structural stability.
GPR103 is a 455-amino-acid protein highly expressed in the brain, retina, trigeminal ganglion, hypothalamus, and vestibular nucleus. In peripheral tissues, it is expressed in the heart, kidney, and testis, and may regulate adrenal function. The hypothalamic neuropeptide 26RFa acts as an endogenous ligand for GPR103.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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