Thermo Fisher Scientific COX18 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human COX18. Recombinant protein control fragment (Product #RP-100830). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:COX18,uniProtId:Q8N8Q8-1,ncbiNodeId:9606,antigenRange:103-165,antigenLength:333,antigenImageFileName:PA5-61990_COX18_Q8N8Q8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61990_COX18_Q8N8Q8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640093

Product Specific Information

Immunogen sequence: AYQHYILAKV ENLQPEIKTI ARHLNQEVAV RANQLGWSKR DARLTYLKNM RRLISELYVR DNC

Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 86%.

Target Information

COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain. Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.