Thermo Fisher Scientific CASC4 Polyclonal Antibody
Human CASC4 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 0.05 mg/mL 농도의 액상 형태로 제공됩니다. HER-2/neu 관련 암 연구에 유용한 연구용 항체입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CASC4. Recombinant protein control fragment (Product # RP-99876) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639303 |
Product Specific Information
Immunogen sequence:
DSHINHNGNP GTSKQNPSSP LQRLIPGSNL DSEPRIQTDI LKQATKDRVS DFHKLKQSRF FDENESPVDP QHGSKLADYN GDDG
Highest antigen sequence identity to the following orthologs:
- Mouse: 83%
- Rat: 82%
Target Information
The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Further characterization of the product of this gene may yield insight into the fundamental biology and pathogenetic effects of HER-2/neu overexpression in human breast and ovarian cancer cells. Alternatively spliced variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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