Thermo Fisher Scientific CTNNBL1 Polyclonal Antibody
Rabbit polyclonal antibody targeting CTNNBL1, validated for IHC and IHC-P applications. Reacts with human and mouse, predicted cross-reactivity with multiple species. Supplied as liquid, 0.25 mg/mL, antigen affinity purified, stored at 4°C. For researc...
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC-P)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human catenin, beta like 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Rat, Bovine, Dog, Horse, Rabbit, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, and Chinese hamster
Target Information
The CTNNBL1 protein is a component of the pre-mRNA-processing factor 19–cell division cycle 5-like (PRP19-CDC5L) complex, which activates pre-mRNA splicing and is integral to the spliceosome. It serves as a nuclear localization sequence binding protein, interacting with activation-induced deaminase and playing a role in antibody diversification. This gene may be associated with obesity development. Alternative splicing results in multiple transcript variants, and a pseudogene exists on the X chromosome. Diseases associated with CTNNBL1 include Immunodeficiency 99 with Hypogammaglobulinemia and Autoimmune Cytopenias.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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