Thermo Fisher Scientific ACD Monoclonal Antibody (OTI2B1), TrueMAB
ACD 단백질을 인식하는 마우스 단클론 항체로 Western blot과 IHC(Paraffin)에 적합합니다. 고순도의 액상 항체로 PBS/BSA/glycerol 완충액에 보존되며 -20°C에서 안정합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B1 |
| Immunogen | Full length human recombinant protein of human ACD produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway.
The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase, which converts orotic acid to orotidine-5'-monophosphate.
The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase, which converts orotidine-5'-monophosphate to uridine monophosphate.
Defects in this gene cause hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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