Thermo Fisher Scientific FMO1 Polyclonal Antibody
FMO1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot 및 Immunocytochemistry에 사용 가능. 고농도(3.13 mg/mL) 액상 형태이며, -20°C에서 보관. 연구용으로 인간 FMO1(aa 363-532) 서열 기반 면역원 사용.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 363–532 of human FMO1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.13 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806701 |
Product Specific Information
Immunogen sequence:
KPTLAIIGLI KPLGSMIPTG ETQARWAVRV LKGVNKLPPP SVMIEEINAR KENKPSWFGL CYCKALQSDY ITYIDELLTY INAKPNLFSM LLTDPHLALT VFFGPCSPYQ FRLTGPGKWE GARNAIMTQW DRTFKVIKAR VVQESPSPFE SFLKVFSFLA LLVAIFLIFL
Positive Samples: Mouse liver
Cellular Location: Endoplasmic reticulum membrane, Microsome membrane
Target Information
Metabolic N-oxidation of diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase. It is subject to an inherited FMO3 polymorphism in humans, resulting in reduced TMA N-oxidation capacity (Trimethylaminuria, fish odor syndrome).
Three forms of the enzyme are encoded by genes clustered in the 1q23–q25 region:
- FMO1: Found in fetal liver
- FMO2: Found in adult liver
- FMO3: Involved in TMA metabolism
Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyze oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 정보: PA5-93278_FMO1_Q01740-1_Rabbit.svg, PA5-93278_FMO1_Q01740-1_Rabbit_PDP.jpeg)
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