Thermo Fisher Scientific GRB 14 Polyclonal Antibody
GRB14 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성 보유하며, Protein A로 정제된 고순도 항체입니다. 연구용으로 성장 및 대사 조절 신호전달 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human GRB14, amino acids 221–320 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The product of this gene belongs to a small family of adapter proteins that interact with receptor tyrosine kinases and signaling molecules.
GRB14 encodes a growth factor receptor-binding protein that interacts with insulin and insulin-like growth factor receptors.
This protein likely inhibits receptor tyrosine kinase signaling, particularly insulin receptor signaling, and may play a role in pathways regulating growth and metabolism.
Transcript variants have been reported for this gene, though their full-length forms have not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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