Thermo Fisher Scientific TP53I3 Monoclonal Antibody (OTI3B11), TrueMAB
TP53I3 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, Western blot 및 IHC(P) 검증 완료. Human 반응성, carrier-free 형태로 제공되어 conjugation 실험에 적합. Lyophilized 형태로 안정적이며, -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B11 |
| Immunogen | Full length human recombinant protein of human TP53I3 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The TP53I3 gene encodes a protein similar to oxidoreductases, enzymes involved in cellular responses to oxidative stress and irradiation. It is induced by the tumor suppressor p53 and participates in p53-mediated cell death. The gene contains a p53 consensus binding site and a downstream pentanucleotide microsatellite sequence, which influences transcriptional activation by p53. Microsatellite polymorphism may be associated with differential cancer susceptibility. Two transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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