Thermo Fisher Scientific CD8 beta Polyclonal Antibody, Biotin
Western blot, ELISA, Immunoprecipitation에 적합한 CD8 beta 폴리클로날 항체. 인간, 마우스, 랫트 반응성. Biotin 결합, Rabbit IgG 유래. 합성 펩타이드(aa 70–120) 면역원 사용. -20°C 보관, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 70–120 on human T-cell surface glycoprotein CD8 Beta chain |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor to recognize antigens presented by antigen-presenting cells (APCs) in the context of class I MHC molecules. The functional coreceptor can be a homodimer (two alpha chains) or a heterodimer (one alpha and one beta chain). Both chains share significant homology with immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms, and multiple alternatively spliced transcript variants have been described. A pseudogene is also located on chromosome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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