Thermo Fisher Scientific Glutamine Synthetase/GLUL Recombinant Mouse Monoclonal Antibody (rGLUL/8621)
Recombinant mouse monoclonal antibody targeting human Glutamine Synthetase (GLUL). Validated for IHC (paraffin) applications. High purity via Protein A/G purification. Supplied in PBS with BSA and sodium azide for stability. Suitable for research use o...
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rGLUL/8621 |
| Immunogen | Recombinant fragment (around aa 1–200) of human GLUL protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Human brain, stomach, or thyroid
- Cellular Location: Cytoplasm, Mitochondrion
Target Information
Glutamine synthase is a member of the glutamine synthetase family. In animals, ammonia incorporation occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays a central role in mammalian nitrogen flow, acting as both a nitrogen donor and acceptor. It also regulates neurotransmitter glutamate metabolism. Due to its multiple roles in cellular metabolism, GS activity and synthesis are tightly regulated, primarily through adenylylation. Its activity is reduced in the cerebral cortex of Alzheimer’s disease brains, especially near senile plaques, and under glucose deprivation conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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