Thermo Fisher Scientific Phospho-GKAP1 (Ser25) Polyclonal Antibody
GKAP1 단백질의 Ser25 인산화 부위를 특이적으로 인식하는 폴리클로날 항체. Western blot 및 IHC(파라핀 절편) 분석에 적합. 인간, 마우스, 랫트 시료 반응. 액상 형태, 1 mg/mL 농도, -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GKAP1 (Accession Q5VSY0), corresponding to amino acid residues around phosphorylated Ser25 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816690 |
Product Specific Information
This antibody detects endogenous levels of GKAP only when phosphorylated at Ser25.
Target Information
The approximately 142 kDa Tankyrase protein is ubiquitously expressed in mammalian cells and is localized to human telomeres. It has homology to ankyrins and to the catalytic domain of poly(ADP-ribose) polymerase (PARP). Tankyrase binds to TRF1 (telomeric repeat binding factor-1), which negatively regulates the maintenance of telomere length.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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