Thermo Fisher Scientific LDLR Recombinant Rabbit Monoclonal Antibody (032)
Thermo Fisher Scientific의 LDLR Recombinant Rabbit Monoclonal Antibody (Clone 032)는 Mouse LDLR에 특이적입니다. ICC/IF, Flow Cytometry, ELISA 등 다양한 응용에 적합하며, 재조합 단일클론 항체로 높은 특이성과 일관성을 제공합니다. 보존제가 없는 PBS 용액 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:50–1:1,000 |
| Flow Cytometry (Flow) | 1:25–1:100 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 032 |
| Immunogen | Recombinant Mouse LDLR protein (Met1–Arg790) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785548 |
Available Conjugated Formats
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the larger rabbit immune repertoire
This antibody specifically recognizes Mouse LDLR/LDL Receptor.
Target Information
The low-density lipoprotein receptor (LDL-R) gene family encodes cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LDL binds at the cell membrane and is internalized, leading to cholesterol release and regulation of HMG CoA reductase activity. Mutations in LDL-R cause familial hypercholesterolemia. LDL-R, along with SCARB1, CLDN1, and CD81, has been identified as an entry factor for Hepatitis C virus. Multiple isoforms of LDL-R are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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