Thermo Fisher Scientific PCCA Polyclonal Antibody
Thermo Fisher Scientific의 PCCA 폴리클로날 항체는 인간 및 마우스 반응성을 가지며, Western blot과 IHC에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PCCA (Accession P05165), corresponding to amino acid residues K694–E728 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815699 |
Product Specific Information
Antibody detects endogenous levels of total PCCA.
Target Information
This protein is a key enzyme in the catabolic pathway of odd-chain fatty acids, isoleucine, threonine, methionine, and valine. It is likely a dodecamer composed of six biotin-containing alpha subunits and six beta subunits located in the mitochondrial matrix.
Defects in PCCA cause propionic acidemia type I (PA-1), a life-threatening disease characterized by episodic vomiting, lethargy, ketosis, neutropenia, thrombocytopenia, hypogammaglobulinemia, developmental retardation, and intolerance to protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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