Thermo Fisher Scientific ZCRB1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–10 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Rat and Bovine

Target Information

ZCRB1 is a nuclear protein first identified in a differential display screen involving morphine-dependence-related genes. Its expression increases following morphine treatment and has been observed to be elevated in HepG2 cells. ZCRB1 contains a CCHC-type zinc finger RNA-binding motif and can interact with the DBA-binding domain of the stem cell regulator C/EBP transcription factors. It is one of the protein components of U11/U12 snRNPs, which are part of the U12-type spliceosome and function as a molecular bridge connecting both ends of the intron, suggesting ZCRB1 may play a key role in U12-type splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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