Thermo Fisher Scientific HMGB2 Polyclonal Antibody
Rabbit 폴리클로날 항체로 HMGB2 단백질을 인식합니다. Western blot 및 IHC(P)에서 검증되었습니다. 다양한 종에서 높은 반응성을 보이며, 4°C 단기 보관 및 -20°C 장기 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–2.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide region of human HMGB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2233034 |
Product Specific Information
- Recommended positive control: Jurkat
- Predicted reactivity: Cow (100%), Dog (100%), Guinea Pig (100%), Horse (100%), Mouse (100%), Rabbit (100%), Rat (100%), Zebrafish (85%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells.
In vitro studies have demonstrated that this protein can efficiently bend DNA and form DNA circles, suggesting a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility.
This protein is also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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