Thermo Fisher Scientific Bcl-X Polyclonal Antibody
Bcl-X 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(P)에서 검증됨. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%) 제품. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 50–100 of Human Bcl-X |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2802913 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
The protein encoded by the BCL-X gene belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in various cellular activities. These proteins are located at the outer mitochondrial membrane and regulate the opening of the mitochondrial membrane channel (VDAC). VDAC controls mitochondrial membrane potential, reactive oxygen species production, and cytochrome C release, all of which are key in apoptosis induction. Alternative splicing results in multiple transcript variants encoding two isoforms — the longer isoform inhibits apoptosis, while the shorter isoform promotes it.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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