Thermo Fisher Scientific nNOS Polyclonal Antibody
Thermo Fisher Scientific의 nNOS Polyclonal Antibody는 인간 시료에서 neuronal Nitric Oxide Synthase를 검출하는 항체입니다. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. -20°C 보관하며, 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues P(19) R K G P P L P N G D T E C(31) of nNOS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2152594 |
Product Specific Information
PA1-4121 detects neuronal Nitric Oxide Synthase in human samples.
PA1-4121 has been successfully used in Western blot procedures.
The PA1-4121 immunogen is a synthetic peptide corresponding to residues P(19) R K G P P L P N G D T E C(31) of nNOS.
Target Information
NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH, and O₂) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin, and heme).
Several distinct NOS isoforms have been described and shown to represent the products of three distinct genes. These include two constitutive Ca²⁺/CaM-dependent forms of NOS:
- NOS1 (ncNOS) – activity first identified in neurons
- NOS3 (ecNOS) – activity first identified in endothelial cells
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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