Thermo Fisher Scientific Caspase 1 Polyclonal Antibody
Caspase-1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 및 마우스 시료에 반응합니다. Western blot과 IHC(P)에서 사용 가능하며, 단백질 G로 정제된 액상 형태입니다. 장기 보관 시 -20°C에서 냉동 보관을 권장합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:10–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide made to an internal portion of the human Caspase-1 protein (between amino acids 15–60) [UniProt P29466] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2069048 |
Product Specific Information
Suggested positive control: antigen standard for CASP1 (transient overexpression lysate), Hela whole cell extract.
Target Information
Caspases are a family of cysteine proteases divided into apoptotic and inflammatory subfamilies. Inflammatory caspases, including caspase-1, -4, -5, and -12, are involved in immune responses rather than cell death. Caspase-1 activates proinflammatory cytokines such as IL-1β and IL-18 and was initially identified as an IL-1β-converting enzyme. It is homologous to the C. elegans cell death gene ced-3, whose overexpression can induce apoptosis in fibroblasts.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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