Thermo Fisher Scientific SPTBN1 Polyclonal Antibody
Human Spectrin beta-1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, 비결합형 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | - | 1 publication |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Spectrin beta-1. Recombinant protein control fragment (Product #RP-89904). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647832 |
Product Specific Information
Immunogen sequence:
PLATSTDHGH NLQTVQLLIK KNQTLQKEIQ GHQPRIDDIF ERSQNIVTDS SSLSAEAIRQ RLADLKQLWG LLIEETEKRH RRLEEAHRAQ QYYFDAAEAE AWMSEQEL
Antigen sequence identity:
- Mouse: 97%
- Rat: 97%
Target Information
Spectrin (Sp), the most abundant erythrocyte membrane skeleton protein, helps maintain the biconcave shape and elasticity of red blood cells. It consists of a 280 kDa alpha subunit and a 246 kDa beta subunit forming a rod-like structure. In other tissues, distinct but homologous alpha and beta subunits (fodrin) exist. The erythrocyte subunits are designated as alpha-1 and beta-1; fodrin subunits as alpha-2 and beta-2. Alternatively spliced forms are denoted epsilon-1, epsilon-2, etc. (e.g., beta-1 epsilon-1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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