Thermo Fisher Scientific RSPO1 Monoclonal Antibody (OTI2B11), TrueMAB
RSPO1 단백질을 인식하는 마우스 단클론 항체로 Western blot에 최적화됨. 인간 유래 단백질 조각(aa 21-263)을 면역원으로 사용. 동결건조 형태로 제공되며, PBS와 트레할로오스 완충액에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 21–263 of human RSPO1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
RSPO1 is a secreted activator protein belonging to the R-spondin family, containing two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces rapid crypt cell proliferation and enhances intestinal epithelial healing, providing protection against chemotherapy-induced damage.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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