Thermo Fisher Scientific ALDH3A2 Monoclonal Antibody (OTI 1B11), TrueMAB

Applications

• Western Blot (WB): 1:500 dilution tested

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Aldh3A2 belongs to the aldehyde dehydrogenase superfamily, enzymes that catalyze oxidation of aliphatic and aromatic aldehydes using NAD(P)(+). These enzymes are involved in detoxifying aldehydes from alcohol metabolism and lipid peroxidation.
Aldh3A2 specifically catalyzes oxidation of long-chain aliphatic aldehydes to fatty acids.
Mutations in the ALDH3A2 gene cause Sjogren-Larrson syndrome, a neurocutaneous disorder characterized by ichthyosis, mental retardation, and spastic diplegia, resulting from abnormal lipid accumulation or defective eicosanoid metabolism.

For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.