Thermo Fisher Scientific Human FGF-18, Animal-Free Recombinant Protein, PeproTech
동물 유래 성분이 없는 재조합 인간 FGF-18 단백질로, E. coli에서 발현된 20.1 kDa 단백질입니다. 세포 증식 활성 검증 완료, 고순도(≥95%) 제품으로 연구용에 적합합니다. 상온 배송 및 -20°C 보관 권장.
- 카탈로그번호
- AF-100-28-xxxxx (2개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human FGF-18, Animal-Free Recombinant Protein, PeproTech
Applications
- Functional Assay (Functional)
Tested Dilution: Assay-dependent
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | AEENVDFRIH VENQTRARDD VSRKQLRLYQ LYSRTSGKHI QVLGRRISAR GEDGDKYAQL LVETDTFGSQ VRIKGKETEF YLCMNRKGKL VGKPDGTSKE CVFIEKVLEN NYTALMSAKY SGWYVGFTKK GRPRKGPKTR ENQQDVHFMK RYPKGQPELQ KPFKYTTVTK RSR |
| Molecular Weight | 20.1 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 95% (by SDS-PAGE and HPLC) |
| Endotoxin Concentration | < 0.1 EU/µg |
| Activity | Determined by cell proliferation assay using Balb/c 3T3 cells. Expected ED50 ≤ 10 ng/ml (≥ 1 x 10^5 units/mg) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human FGF-18 derived from E. coli is a 20.1 kDa protein consisting of 173 amino acid residues, resulting from C-terminal truncation of the full-length protein.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in various biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion.
In vitro studies show that this protein induces neurite outgrowth in PC12 cells. Studies in mouse and chick suggest that FGF18 is a pleiotropic growth factor stimulating proliferation in tissues such as the liver and small intestine. Knockout studies in mice indicate its role in regulating proliferation and differentiation of midline cerebellar structures.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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