
Thermo Fisher Scientific DTNA Monoclonal Antibody (OTI1C2), TrueMAB
DTNA 단백질을 인식하는 Mouse IgG2a 단클론 항체로, Western blot, ICC/IF, Flow Cytometry에 사용 가능. 사람 시료 반응성. 무보존제, 동결건조 형태로 제공되며, 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C2 |
| Immunogen | Full length human recombinant protein of human DTNA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The DTNA protein belongs to the dystrobrevin subfamily of the dystrophin family and is a component of the dystrophin-associated protein complex (DPC).
DPC includes dystrophin and several integral and peripheral membrane proteins such as dystroglycans, sarcoglycans, syntrophins, and alpha- and beta-dystrobrevin.
Disruption of DPC is associated with various forms of muscular dystrophy.
Mutations in DTNA are linked to left ventricular noncompaction with congenital heart defects.
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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