Thermo Fisher Scientific CHMP2B Polyclonal Antibody
CHMP2B 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, IP 등 다양한 응용에 적합. 1 mg/mL 농도의 액상 형태로 제공되며, 4°C에서 보관. FFPE 조직 IHC 시 citrate buffer(pH 6.0) 전처리 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 163–213 of human Charged Multivesicular Body Protein 2B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Predicted to react with X. laevis, X. tropicalis, Chicken, Bovine, and Orangutan (based on 100% sequence identity)
Target Information
CHMP2B (Charged Multivesicular Body Protein 2B), also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. It is widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta, and leukocytes. CHMP2B interacts directly with CHMP2A and VPS4 for disassembly of the ESCRT-III complex.
Defects in the CHMP2B gene are associated with chromosome 3-linked frontotemporal dementia (FTD3).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: A304-501A-M_CHMP2B_Q9UQN3-1_Rabbit.svg, A304-501A-M_CHMP2B_Q9UQN3-1_Rabbit_PDP.jpeg)
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