Thermo Fisher Scientific TRAIL-R3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 150-238 of human TNFRSF10C (NP_0038322) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TRAIL-R3 (CD263),uniProtId:O14798-1,ncbiNodeId:9606,antigenRange:150-238,antigenLength:259,antigenImageFileName:PA5-88119_TRAIL-R3_CD263_O14798-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88119_TRAIL-R3_CD263_O14798-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.51 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804666

Product Specific Information

Immunogen sequence: VEEFGANATV ETPAAEETMN TSPGTPAPAA EETMNTSPGT PAPAAEETMT TSPGTPAPAA EETMTTSPGT PAPAAEETMT TSPGTPASS

Positive Samples: LO2, Mouse lung, Rat lung; Cellular Location: Cell membrane, GPI-anchor, Lipid-anchor

Target Information

TRAIL-R3 (CD263) is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.