Thermo Fisher Scientific PSMB10 Polyclonal Antibody
Human PSMB10 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot에 적합합니다. 중간 영역 합성 펩타이드로부터 유래되었으며, 0.5 mg/mL 농도의 액상 형태입니다. Affinity Chromatography로 정제되었으며, PBS(2% sucrose) 버퍼에 보관됩니다.
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- PA544572
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human PSMB10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608845 |
Product Specific Information
Peptide sequence:
DLTGPQLYGV HPHGSYSRLP FTALGSGQDA ALAVLEDRFQ PNMTLEAAQG
Sequence homology:
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%
Target Information
The 20S proteasome is a protease complex responsible for cytosolic protein degradation and generation of peptide ligands for MHC class I molecules. Upon IFN-gamma stimulation, three constitutively expressed subunits (LMP2, LMP7, MECL-1/LMP10) are induced to form immunoproteasomes, enhancing class I antigen processing and presentation.
Independent assortment of these subunits can lead to up to 36 unique proteasome subsets, contributing to differences in substrate cleavage specificity between constitutive and immuno-proteasomes.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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