Thermo Fisher Scientific SH3BP2 Polyclonal Antibody
SH3BP2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 IHC에 사용 가능. 인간 시료에 반응하며, 합성 펩타이드 면역원 기반. 액상 형태로 -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human SH3BP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608286 |
Product Specific Information
Peptide sequence:
RQPSQADTGG DDSDEDYEKV PLPNSVFVNT TESCEVERLF KATSPRGEPQ
Sequence homology:
Cow: 85%
Dog: 93%
Guinea Pig: 93%
Human: 100%
Mouse: 100%
Rabbit: 93%
Rat: 100%
Target Information
The protein encoded by this gene contains an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. It binds to the SH3 domains of several proteins including ABL1 and SYK tyrosine kinases, functioning as a cytoplasmic adaptor protein that positively regulates transcriptional activity in T cells, NK cells, and basophilic cells. Mutations in this gene are associated with cherubism. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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