Thermo Fisher Scientific ELOVL6 Polyclonal Antibody
Thermo Fisher Scientific의 ELOVL6 Polyclonal Antibody는 인간 ELOVL6 단백질을 인식하는 토끼 IgG 항체입니다. IHC(P)에서 1:20~1:50 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 지방산 합성 연구 및 대사 관련 연구용에 적합합니다.
- 카탈로그번호
- PA559954
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ELOVL6. Recombinant protein control fragment (Product #RP-91275). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641001 |
Product Specific Information
- Immunogen sequence: VLTLQEYEFE KQFNENEAIQ WMQENWKKS
- Highest antigen sequence identity: Mouse - 100%, Rat - 100%
Target Information
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1.
Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of the fatty acyl-CoA elongase gene family that converts palmitic to stearic acid.
It is a known target of SREBP-1 and plays an important role in de novo synthesis of long-chain saturated and monounsaturated fatty acids, in conjunction with fatty acid synthase and stearoyl-CoA desaturase.
ELOVL6 is predicted to be important for tissue fatty acid composition.
Recent studies suggest that inhibition of this elongase could be a potential therapeutic approach for ameliorating insulin resistance, diabetes, and cardiovascular risks, even in obesity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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