Thermo Fisher Scientific FNBP3 Polyclonal Antibody
FNBP3 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. WB, IHC, ICC, ELISA 등 다양한 응용 가능. KLH 결합 합성 펩타이드(aa 851-957)로 면역원 제작. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Thermo Fisher Scientific FNBP3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human FNBP3, amino acids 851–957 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS (pH 7.4), with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FNBP3 (Formin-binding protein 3) is a 957 amino acid protein encoded by the human gene PRPF40A. It belongs to the PRPF40 family and contains five FF domains and two WW domains.
Nuclear proteins containing WW and FF interaction modules bind to splicing factors and RNA polymerase II, potentially linking transcription with splicing.
Through its WW domains, FNBP3 binds to Formin proline-rich regions. Also known as Pre-mRNA-processing factor 40 homolog A, FNBP3 interacts with the WASL/N-WASP complex and inhibits its translocation from nucleus to cytoplasm, thus suppressing its cytoplasmic function.
FNBP3 is widely expressed across tissues and localized to nuclear speckles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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