Thermo Fisher Scientific CLEC12A Monoclonal Antibody (687317)
Human CLEC12A (CD371) 단백질을 인식하는 Mouse IgG2b 단일클론 항체. Flow Cytometry에 적합하며, 단백질 A/G로 정제된 동결건조 형태. PBS + 5% 트레할로스 버퍼에 보관하며, -20°C에서 저장 권장.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 2.5 µg per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 687317 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human MICL/CLEC12A (Thr67–Ala265) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607503 |
Product Specific Information
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
Target Information
CD371 (also known as CLEC12A or Myeloid Inhibitory C-type Lectin-like receptor, MICL) is a highly glycosylated transmembrane receptor with a cytoplasmic ITIM that associates with SHP1 and SHP2.
It is mainly expressed on granulocytes, monocytes, macrophages, and dendritic cells (including plasmacytoid dendritic cells).
Expression on NK cells remains controversial. Although its function is not fully understood, studies suggest a role in inflammation and LPS activation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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