Thermo Fisher Scientific LRRC26 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

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Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LRRC26. Recombinant protein control fragment (Product #RP-100074). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LRRC26,uniProtId:Q2I0M4-1,ncbiNodeId:9606,antigenRange:44-85,antigenLength:334,antigenImageFileName:PA5-63285_LRRC26_Q2I0M4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63285_LRRC26_Q2I0M4-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643502

Product Specific Information

Immunogen sequence: PEVCTCVPGG LASCSALSLP AVPPGLSLRL RALLLDHNRV RA

Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 67%.

Target Information

The LRRC26 protein was initially identified as a cytokeratin-associated protein whose expression was elevated in multiple cancer cell lines and cancer specimens as well in normal prostate and salivary gland tissues. LRRC26 was later found to negatively regulate the NF-kappaB activation and suppresses tumor growth and metastasis. LRRC26 can also act to selectively alter the efficacy of large conductance calcium-activated K (BK) channels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.