Thermo Fisher Scientific IDO2/Indoleamine 2,3-dioxygenase 2 Monoclonal Antibody (IDO2/2639)
Human IDO2 단백질을 인식하는 Mouse 모노클로날 항체로, IHC, ELISA, Peptide Array 등 다양한 응용에 사용 가능. Recombinant fragment(aa 200-350)를 면역원으로 제작되었으며, 24개월 안정성 보장. 단백질 A/G 정제, PBS+BSA buffer, 4°C 보관.
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Thermo Fisher Scientific IDO2/Indoleamine 2,3-dioxygenase 2 Monoclonal Antibody (IDO2/2639)
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL | - |
| ELISA | Assay-dependent | - |
| Peptide Array | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IDO2/2639 |
| Immunogen | Recombinant fragment (around aa 200–350) of human IDO2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Antibody is stable for 24 months.
- Positive Control: Human placenta or liver
- Cellular Localization: Cytoplasm
Specificity Comments:
IDO2 is a presumptive immunomodulatory gene based on its close structural relationship to IDO1 and its expression in a variety of antigen-presenting cell types. Both IDO1 and IDO2 catabolize tryptophan to kynurenine. Biochemical studies indicate that both enzymes are similarly robust in catabolic activity, though the in vitro conditions for IDO2 differ somewhat from IDO1. Further research is needed to confirm IDO2’s activity in human dendritic cells. Distinct expression patterns and extracellular response suggest non-redundant functions between IDO1 and IDO2.
Target Information
Along with the enzymes encoded by the INDO and TDO2 genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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