Thermo Fisher Scientific ENO1 Monoclonal Antibody (9E4)

Applications

Western Blot (WB)

• Tested Dilution: 1–5 µg/mL

ELISA

• Tested Dilution: 10 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MSILKIHARE IFDSRGNPTV EVDLFTSKGL FRAAVPSGAS TGIYEALELR DNDKTRYMGK GVSKAVEHIN KTIAPALVSK KLNVTEQEKI DKLMIEMDGT ENKSKFGANA ILGVSLAVCK AGAVEKGVPL YRHIADLAGN SEVILPVPAF NVINGGSHAG NKLAMQEFMI LPVGAANFRE AMRIGAEVYH NLKNVIKEKY GKDATNVGDE GGFAPNILEN KEGLELLKTA IGKAGYTDKV VIGMDVAASE FFRSGKYDLD FKSPDDPSRY ISPDQLADLY KSFIKDYPVV SIEDPFDQDD WGAWQKFTAS AGIQVVGDDL TVTNPKRIAK AVNEKSCNCL LLKVNQIGSV TESLQACKLA QANGWGVMVS HRSGETEDTF IADLVVGLCT GQIKTGAPCR SERLAKYNQL LRIEEELGSK AKFAGRNFRN PLAK

Target Information

Enolase (2-phosphogly-cerate hydrolyase or phosphopyruvate hydrates) is a glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. It consists of three subunits: alpha, beta, and gamma.
Non-Neuronal Enolase (ENO1) is an isoform composed of two alpha subunits. The ENO1 gene also encodes tau-crystallin, a structural lens protein.
ENO1 plays roles in:

• Glycolysis and energy metabolism
• Growth control and hypoxia tolerance
• Allergic responses and plasminogen activation
• Diagnostic marker for tumors and hypoxic brain injury
• Marker for endometriosis and autoimmune diseases (e.g., Hashimoto encephalopathy)

Antibodies against alpha-enolase are found in sera from patients with cancer-associated retinopathy syndrome (CAR) and other malignancies.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.