Thermo Fisher Scientific TK1 Recombinant Rabbit Monoclonal Antibody (6F6)
인간 TK1 단백질을 인식하는 재조합 토끼 단일클론 항체. Western blot, ICC/IF, Flow cytometry, ELISA에 사용 가능. 높은 특이성과 재현성을 제공하며, 연구용으로 최적화된 액상 항체.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6F6 |
| Immunogen | A synthesized peptide derived from Human TK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092521 |
Target Information
Thymidine Kinase (TK1) is a highly conserved phosphotransferase present in most living cells. It catalyzes the phosphorylation reaction:
deoxythymidine + ATP → deoxythymidine 5'-phosphate + ADP,
thus playing a key role in incorporating deoxythymidine into DNA. TK1 is essential for the activity of several antiviral drugs, such as azidothymidine (AZT), and is used in hybridoma cell line selection during monoclonal antibody production. Clinically, TK1 is expressed primarily during cell division, making it a valuable marker in proliferation studies.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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