Thermo Fisher Scientific GIPR Recombinant Mouse Monoclonal Antibody (12C6)

Applications

Tested Dilution

Publications

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Mouse / IgG2a

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

12C6

Immunogen

Recombinant Mouse Gipr protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.03% Proclin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

RRID

AB_3093858

Target Information

GIPR encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.